Check made out to order X 
Address to send check: 
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<span fr-original-style="font-size: 14px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:14px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Whether you attend or not, this is the premier event for our community which moves scientific knowledge forward toward treatments! Help make this a success today! <span fr-original-style="font-size: 14px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:14px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Multisystemic Smooth Muscle Dysfunction Syndrome (MSMDS) is a rare and life threatening-condition, primarily diagnosed in children. Raising awareness about it is crucial and so is taking action. That’s why ACTA2 Alliance is asking you to raise $500 to support our 2025 International Research Conference. <span fr-original-style="font-size: 11pt; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:11pt;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Even if it feels ambitious, raising $500 in ten days is an achievable goal. Just follow the roadmap of actions below and you’ll get there in no time!  <span fr-original-style="font-size: 11pt; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:11pt;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Pick your favorite ideas, repeat them, tweak them... make them your own! Before you know it, you will be playing a vital role in advancing MSMDS and improving the life of our loved ones. <h2><span fr-original-style="font-size: 18px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 700; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:18px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:700;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">How can you raise $500 in 10 days?</h2><ul><li style="font-family:Arial;font-size:14px;box-sizing:inherit"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 1- Kick start your fundraiser with a personal donation.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-family:Arial;font-size:14px"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 2- Make a list of 30+ people that you’re going to ask to donate. Then reach out to three family members to donate $25 or more.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-size:14px;font-family:Arial"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 3- Ask 5 friends to donate $20 or more.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-size:14px;font-family:Arial"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 4- Share your fundraiser on social media.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-size:14px;font-family:Arial"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 5- Ask 5 people in your community to donate $10 or more.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-size:14px;font-family:Arial"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 6- Ask a local business to donate $25 or more.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-size:14px;font-family:Arial"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 7- Ask 5 co-workers to donate $20 or more.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-size:14px;font-family:Arial"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 8- Ask your company to help contribute $100 or more.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-size:14px;font-family:Arial"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 9- Ask someone whose cause you have supported to donate $25 or more.</li><li style="line-height:1.38;margin-top:14pt;margin-right:0px;margin-bottom:0pt;width:100%;box-sizing:inherit;color:rgb(0, 0, 0);font-size:14px;font-family:Arial"><span fr-original-style="color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Day 10-Share your fundraiser on social media with updates about your progress <span fr-original-style="font-size: 14px; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:14px;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">towards your goa<span fr-original-style="font-size: 11pt; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:11pt;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">l.</li></ul> You won’t be doing this alone! The board members of ACTA2 Alliance, also parents of affected children, are stepping up and following this same roadmap to raise funds. They have already picked their favorite strategies and are leading the way. Now, they invite you to join them so that, together, we can reach our fundraising goal and make an impact for MSMDS research.<h2><span fr-original-style="font-size: 18px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 700; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:18px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:700;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">The Goal: $10,000 in 10 Days</h2><span fr-original-style="font-size: 14px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:14px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">The III MSMDS International Conference will take place in the Boston area from June 5 to 7. Clinicians and researchers from around the world will attend, along with dozens of MSMDS families.  <span fr-original-style="font-size: 14px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:14px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">Your fundraising <span fr-original-style="letter-spacing: 0.25px; orphans: 2; text-align: left; text-indent: 0px; text-transform: none; widows: 2; word-spacing: 0px; -webkit-text-stroke-width: 0px; float: none; font-size: 14px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap; display: inline !important;" style="letter-spacing:0.25px;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;float:none;font-size:14px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;display:inline !important;box-sizing:inherit">efforts <span fr-original-style="font-size: 14px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:14px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">will directly impact our ability to provide the best scientific and medical knowledge to the international community, leading to earlier diagnoses and better care for those affected by MSMDS. <span fr-original-style="font-size: 14px; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 400; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:14px;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:400;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">  Thank you for considering any action, no matter how small, to support our community.  <span fr-original-style="font-size: 11pt; font-family: Arial; color: rgb(0, 0, 0); background-color: transparent; font-weight: 700; font-style: normal; font-variant: normal; text-decoration: none; vertical-align: baseline; white-space: pre-wrap;" style="font-size:11pt;font-family:Arial;color:rgb(0, 0, 0);background-color:transparent;font-weight:700;font-style:normal;font-variant:normal;text-decoration:none;vertical-align:baseline;white-space:pre-wrap;box-sizing:inherit">ACTA2 Alliance

Dear <span contenteditable="false" data-custom-variable="{{firstname}}" fr-original-class="fr-deletable styled-tag-chip" fr-original-style style="background-color:rgb(248, 248, 255);border:1px solid rgb(191, 191, 255);border-radius:4px;color:rgb(42, 42, 196);padding:1px 8px;font-size:11px;display:inline-block;margin:0px;overflow-wrap:anywhere;user-select:none;box-sizing:inherit">First name, We can't thank you enough for your generous contribution to our 2025 International Research Conference fundraiser! Your support means the world to our small community and brings us one step closer to advancing research and care for those affected by Multisystemic Smooth Muscle Dysfunction Syndrome (MSMDS). We’ll keep you updated on the impact of your generosity as we move closer to the conference. In the meantime, please feel free to send our campaign with others who might want to support this cause.  If you want to help further, you can share our updates in <a href="https://www.facebook.com/Acta2Alliance" rel="noopener noreferrer" style="text-decoration-color:initial;user-select:auto;box-sizing:inherit" target="_blank">Facebook</a> and <a href="https://www.instagram.com/acta2alliance/" rel="noopener noreferrer" style="text-decoration-color:initial;user-select:auto;box-sizing:inherit" target="_blank">Instagram</a> and <a href="https://mailchi.mp/f875ad67ff84/mailing-list-sign-up-page" rel="noopener noreferrer" style="text-decoration-color:initial;user-select:auto;box-sizing:inherit" target="_blank">join our mailing list here</a>. With heartfelt gratitude, Angela Cas GuerraChair, Fundraising Committee<a href="mailto:angela@acta2alliance.org" style="text-decoration-color:initial;user-select:auto;box-sizing:inherit">angela@acta2alliance.org</a>ACTA2 Alliance

Hello First name,
 
 Thank you from the bottom of our hearts for registering to fundraise for our cause. Your efforts will make a significant impact, and we are excited to have you as part of our fundraising team. 👏
 
 💡 Here are some tips for sharing your campaign:
 <ol>
 <li>Personalize Your Story: Share why this cause is important to you. Personal stories resonate more with potential donors.</li>
 <li>Use Social Media: Post about your campaign on Facebook, Instagram, X, and LinkedIn. Include the campaign link and a compelling image or video.</li>
 <li>Email Your Network: Send a personal email to friends, family, and colleagues explaining why you are fundraising and how they can help.</li>
 <li>Regular Updates: Keep your supporters informed with updates on your progress and any milestones you reach. This keeps them engaged and more likely to share your campaign.</li>
 </ol>
 Angela Cas Guerra msmds@acta2alliance.org

Whether you attend or not, this is the premier event for our community which moves scientific knowledge forward toward treatments! Help make this a success today! Multisystemic Smooth Muscle Dysfunction Syndrome (MSMDS) is a rare and life threatening-condition, primarily diagnosed in children. Raising awareness about it is crucial and so is taking action. That’s why ACTA2 Alliance is asking you to raise $500 to support our 2025 International Research Conference. Even if it feels ambitious, raising $500 in ten days is an achievable goal. Just follow the roadmap of actions below and you’ll get there in no time!  Pick your favorite ideas, repeat them, tweak them... make them your own! Before you know it, you will be playing a vital role in advancing MSMDS and improving the life of our loved ones. How can you raise $500 in 10 days?<ul><li>Day 1- Kick start your fundraiser with a personal donation.</li><li>Day 2- Make a list of 30+ people that you’re going to ask to donate. Then reach out to three family members to donate $25 or more.</li><li>Day 3- Ask 5 friends to donate $20 or more.</li><li>Day 4- Share your fundraiser on social media.</li><li>Day 5- Ask 5 people in your community to donate $10 or more.</li><li>Day 6- Ask a local business to donate $25 or more.</li><li>Day 7- Ask 5 co-workers to donate $20 or more.</li><li>Day 8- Ask your company to help contribute $100 or more.</li><li>Day 9- Ask someone whose cause you have supported to donate $25 or more.</li><li>Day 10-Share your fundraiser on social media with updates about your progress towards your goal.</li></ul> You won’t be doing this alone! The board members of ACTA2 Alliance, also parents of affected children, are stepping up and following this same roadmap to raise funds. They have already picked their favorite strategies and are leading the way. Now, they invite you to join them so that, together, we can reach our fundraising goal and make an impact for MSMDS research.The Goal: $10,000 in 10 DaysThe III MSMDS International Conference will take place in the Boston area from June 5 to 7. Clinicians and researchers from around the world will attend, along with dozens of MSMDS families.  Your fundraising efforts will directly impact our ability to provide the best scientific and medical knowledge to the international community, leading to earlier diagnoses and better care for those affected by MSMDS.   Thank you for considering any action, no matter how small, to support our community.  ACTA2 Alliance

Raise $500 to support our International Research Conference

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ACTA2 Alliance Inc.

### Context Profile for ACTA2 Alliance Inc.

#### 1. Organization Mission & Cause
**Mission**: The ACTA2 Alliance Inc. is dedicated to supporting research and awareness for Multisystemic Smooth Muscle Dysfunction Syndrome (MSMDS), a rare genetic disorder caused by mutations in the ACTA2 gene. Their mission is to transform the lives of children affected by this condition through advocacy, funding research, and facilitating the development of effective treatments.

**Cause**: The organization aims to bring life-saving research from the lab to children suffering from MSMDS, highlighting the urgent need for innovative therapies that can alleviate the challenges these children face daily.

#### 2. Type of Activities
- **Research Funding**: The organization actively supports scientific research aimed at developing treatments for MSMDS.
- **Awareness Campaigns**: They engage in efforts to raise awareness about MSMDS and its impact on affected families.
- **Community Support**: They provide resources and information to families dealing with MSMDS, fostering a supportive community.

#### 3. Tone of Voice
The tone of voice used by ACTA2 Alliance Inc. is:
- **Inspiring**: The language is uplifting, focusing on hope and the potential for breakthroughs in treatment.
- **Urgent**: There is a sense of immediacy in their messaging, emphasizing the critical need for support and funding.
- **Empathetic**: The organization communicates with a deep understanding of the challenges faced by families affected by MSMDS, fostering a connection with their audience.

#### 4. Emoji Usage
The analysis of the website and recent campaign materials shows:
- **No Emoji Usage**: The organization does not use emojis in their communications. Their content is straightforward and professional, focusing on the seriousness of the cause.

#### 5. Key Facts
- **Founding Information**: Specific founding details are not provided on the website; further research may be needed for this information.
- **Scale**: The organization appears to be small-scale, focusing on a niche area of research and support.
- **Impact Metrics**: While specific metrics are not detailed on the website, the emphasis on funding research and community support suggests a commitment to measurable outcomes in treatment development.
- **Volunteer Information**: No specific volunteer opportunities are mentioned, but the organization likely welcomes community involvement in their initiatives.

#### 6. Writing Guidelines
Based on the existing content patterns observed:
- **Use Clear and Direct Language**: Avoid jargon; communicate complex ideas simply.
- **Focus on Emotional Appeal**: Highlight stories of affected families and the impact of donations.
- **Encourage Action**: Use strong calls to action that emphasize urgency and the importance of support.
- **Maintain a Professional Yet Compassionate Tone**: Balance professionalism with empathy to connect with the audience effectively.

This context profile serves as a foundation for generating personalized and impactful content for ACTA2 Alliance Inc., aligning with their mission and communication style.

I give authorization to the ACTA2 Alliance Foundation to send me updates on the impact of my gift and other related news.

ACTA2 Alliance Inc.

Raise $500 to support our International Research Conference

You'll receive a tax receipt for making a donation.