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<div style="color:rgb(34, 34, 34);font-family:Arial, Helvetica, sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;background-color:rgb(255, 255, 255);text-decoration-thickness:initial;text-decoration-style:initial;text-decoration-color:initial;line-height:1.5;box-sizing:inherit"><table><tbody><tr><td><table><tbody><tr><td><span fr-original-style="color: rgb(251, 160, 38); font-family: &quot;Barlow Condensed&quot;, sans-serif; font-size: 18pt; font-weight: 700; letter-spacing: 0.25px; text-align: justify;" style="color:rgb(251, 160, 38);font-family:&quot;Barlow Condensed&quot;, sans-serif;font-size:18pt;font-weight:700;letter-spacing:0.25px;text-align:justify;box-sizing:inherit">Projet Propo-Onco Project</span></td></tr></tbody></table></td></tr></tbody></table></div><div style="color:rgb(34, 34, 34);font-family:Arial, Helvetica, sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;background-color:rgb(255, 255, 255);text-decoration-thickness:initial;text-decoration-style:initial;text-decoration-color:initial;line-height:1.5;box-sizing:inherit"><br /></div><div style="color:rgb(34, 34, 34);font-family:Arial, Helvetica, sans-serif;font-size:small;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:start;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;background-color:rgb(255, 255, 255);text-decoration-thickness:initial;text-decoration-style:initial;text-decoration-color:initial;line-height:1.5;box-sizing:inherit"><div style="line-height:1.5;box-sizing:inherit"><div style="line-height:1.5;box-sizing:inherit"><div style="color:rgb(34, 34, 34);font-family:&quot;Google Sans&quot;, Roboto, RobotoDraft, Helvetica, Arial, sans-serif;line-height:1.5;box-sizing:inherit"><table><tbody><tr><td><table><tbody><tr><td><p style="margin:0px;line-height:1.5;box-sizing:inherit;color:rgb(0, 0, 0)"><img src="https://res.cloudinary.com/hxn9dbuhd/image/upload/v1741012999/s4wuk4nk7rcdsijaqog7.png" alt style="background-image:url(&quot;https://ci3.googleusercontent.com/meips/ADKq_NYV2Or50ypV91q2_cRmF0R7YnTaptikVlQKU3MYUxIPOjCgL4OiX1XeB3Ljtr3ED_nQp6KBgm7p9KO1TspYnkzjeCUBICL0nmCBvjg_4ehtXl8uFUnoauN1bgzRHBQ6mqcNR2ik6yRjBWHdbkC79Q=s0-d-e1-ft#https://www.gstatic.com/images/icons/material/system_gm/1x/arrow_drop_down_black_20dp.png&quot;);position:relative;max-width:100%;cursor:pointer;padding:0px 1px;user-select:none;box-sizing:inherit" /><span fr-original-style="background-color: transparent; color: rgb(251, 160, 38); font-family: &quot;Barlow Condensed&quot;, sans-serif; font-size: 18pt; font-weight: 700; letter-spacing: 0.25px; text-align: justify;" style="background-color:transparent;color:rgb(251, 160, 38);font-family:&quot;Barlow Condensed&quot;, sans-serif;font-size:18pt;font-weight:700;letter-spacing:0.25px;text-align:justify;box-sizing:inherit">Science et abeilles</span></p><div style="box-sizing:inherit;margin:0px;line-height:1.5;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><span fr-original-style="box-sizing: inherit; font-size: 14.9925pt; font-family: Barlow, sans-serif; color: rgb(12, 20, 51); background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:14.9925pt;font-family:Barlow, sans-serif;color:rgb(12, 20, 51);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">Le laboratoire de Francis Rodier, chercheur au CRCHUM qui se spécialise dans l’exploration de la vie et de la mort des cellules cancéreuses en réponse aux traitements anticancéreux, se joint à Bee-O-Pharm afin d'évaluer le potentiel d’utilisation de la « propolis ». Cette équipe évaluera l'impact de la propolis sur les cellules cancéreuses sénescentes, un état de vieillissement prématuré causé par la chimiothérapie, avec l'objectif d’améliorer l’efficacité des traitements eux-mêmes </span><span fr-original-style="font-size: 19.99px;;box-sizing: inherit; font-size: 14.9925pt; font-family: Barlow, sans-serif; color: rgb(12, 20, 51); background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:14.9925pt;font-family:Barlow, sans-serif;color:rgb(12, 20, 51);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">et d'améliorer la qualité de vie des patients par la réduction des effets secondaires. </span></div><span fr-original-style="color: rgb(80, 0, 80);" style="color:rgb(80, 0, 80);box-sizing:inherit"><p style="box-sizing:inherit;margin:21.128pt 46.3994pt 0pt 0px;line-height:1.35014;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-indent:0.749626pt;text-align:justify;color:rgb(0, 0, 0)"><span fr-original-style="box-sizing: inherit; font-size: 18px; font-family: &quot;Barlow Condensed&quot;, sans-serif; color: rgb(251, 160, 38); background-color: transparent; font-weight: 700; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:18px;font-family:&quot;Barlow Condensed&quot;, sans-serif;color:rgb(251, 160, 38);background-color:transparent;font-weight:700;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">QU’EST-CE QUE LA PROPOLIS?</span></p></span><div style="box-sizing:inherit;margin:0pt 0px;line-height:1.3928;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><span fr-original-style="box-sizing: inherit; font-size: 13.995pt; font-family: Barlow, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:13.995pt;font-family:Barlow, sans-serif;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">La propolis est une résine récoltée et transformée par les abeilles qui constitue le « remède » des abeilles, leur propre médicament. Les abeilles fabriquent la propolis en mélangeant la résine à leur cire et leur salive, elles vont ensuite tapisser l’intérieur de la ruche entièrement de cette propolis. Certaines propriétés de la propolis bien connues aujourd’hui incluent son potentiel </span><span fr-original-style="box-sizing: inherit; font-size: 13.995pt; font-family: Barlow, sans-serif; background-color: transparent; font-weight: 700; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:13.995pt;font-family:Barlow, sans-serif;background-color:transparent;font-weight:700;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">anti bactérien, anti-viral et anti-fongique, </span><span fr-original-style="box-sizing: inherit; font-size: 13.995pt; font-family: Barlow, sans-serif; background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:13.995pt;font-family:Barlow, sans-serif;background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">assurant ainsi un état de salubrité maximal à la ruche.  <br /></span></div><span fr-original-style="color: rgb(80, 0, 80);" style="color:rgb(80, 0, 80);box-sizing:inherit"><div style="box-sizing:inherit;margin:0pt 57.2456pt 0pt 0px;line-height:1.2;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><span fr-original-style="box-sizing: inherit; font-size: 16.995pt; font-family: &quot;Barlow Condensed&quot;, sans-serif; color: rgb(255, 255, 255); background-color: transparent; font-weight: 700; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:16.995pt;font-family:&quot;Barlow Condensed&quot;, sans-serif;color:rgb(255, 255, 255);background-color:transparent;font-weight:700;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">PROPOLIS : LE TRÉSOR DES ABEILLES, UNE PROMESSE POUR M </span></div><div style="box-sizing:inherit;margin:0pt 57.2456pt 0pt 0px;line-height:1.2;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><br /></div></span><div style="box-sizing:inherit;margin:0pt 57.2456pt 0pt 0px;line-height:1.2;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><span fr-original-style="box-sizing: inherit; font-size: 15pt; font-family: &quot;Barlow Condensed&quot;, sans-serif; background-color: transparent; font-weight: 700; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:15pt;font-family:&quot;Barlow Condensed&quot;, sans-serif;background-color:transparent;font-weight:700;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">Voici certains mécanismes d'action proposés de la propolis dont certains seront validés scientifiquement par le projet proposé:</span></div><span fr-original-style="color: rgb(80, 0, 80);" style="color:rgb(80, 0, 80);box-sizing:inherit"><ul><li style="margin-left:15px;box-sizing:inherit"><div style="box-sizing:inherit;margin:0px;line-height:1.5"><span fr-original-style="box-sizing: inherit; font-size: 14.9925pt; font-family: Barlow, sans-serif; color: rgb(12, 20, 51); background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:14.9925pt;font-family:Barlow, sans-serif;color:rgb(12, 20, 51);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">Inhibition de la prolifération cellulaire: La propolis peut arrêter le cycle cellulaire dans les tissus cancéreux, réduisant ainsi la multiplication des cellules malignes.</span></div></li><li style="margin-left:15px;box-sizing:inherit"><div style="box-sizing:inherit;margin:0px;line-height:1.5"><span fr-original-style="box-sizing: inherit; font-size: 14.9925pt; font-family: Barlow, sans-serif; color: rgb(12, 20, 51); background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:14.9925pt;font-family:Barlow, sans-serif;color:rgb(12, 20, 51);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">Induction de l'apoptose: Certains composés de la propolis, tels que l'artépilline C, favorisent l'apoptose (mort programmée) des cellules cancéreuses, contribuant à limiter la progression tumorale. </span></div></li><li style="margin-left:15px;box-sizing:inherit"><div style="box-sizing:inherit;margin:0px;line-height:1.5"><span fr-original-style="box-sizing: inherit; font-size: 14.9925pt; font-family: Barlow, sans-serif; color: rgb(12, 20, 51); background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:14.9925pt;font-family:Barlow, sans-serif;color:rgb(12, 20, 51);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">Effet anti-angiogénique: La propolis peut inhiber la formation de nouveaux vaisseaux sanguins nécessaires à la croissance tumorale, affaiblissant ainsi la tumeur en réduisant son apport en nutriments. </span></div></li><li style="margin-left:15px;box-sizing:inherit"><div style="box-sizing:inherit;margin:0px;line-height:1.5"><span fr-original-style="box-sizing: inherit; font-size: 14.9925pt; font-family: Barlow, sans-serif; color: rgb(12, 20, 51); background-color: transparent; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:14.9925pt;font-family:Barlow, sans-serif;color:rgb(12, 20, 51);background-color:transparent;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">Action anti-métastatique: Des études suggèrent que la propolis pourrait prévenir et réduire le nombre et le volume des métastases, limitant la propagation du cancer. </span></div></li></ul><div style="box-sizing:inherit;margin:0px;line-height:1.5;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><br /></div></span><div style="box-sizing:inherit;margin:0px;line-height:1.5;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><span fr-original-style="box-sizing: inherit; font-size: 15pt; font-family: Barlow, sans-serif; background-color: transparent; font-weight: 700; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:15pt;font-family:Barlow, sans-serif;background-color:transparent;font-weight:700;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">Le projet de recherche vise dans un premier temps à confirmer l'action du propolis sur les cellules cancéreuses en utilisant les plateformes scientifiques et l’expertise bien établies de l’Institut du cancer de Montréal. </span></div><div style="box-sizing:inherit;margin:0px;line-height:1.5;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><br /></div><div style="box-sizing:inherit;margin:0px;line-height:1.5;font-family:Roboto;font-size:14px;letter-spacing:0.25px;text-align:justify"><span fr-original-style="box-sizing: inherit; font-size: 15pt; font-family: Barlow, sans-serif; background-color: transparent; font-weight: 700; font-variant-numeric: normal; font-variant-east-asian: normal; font-variant-alternates: normal; vertical-align: baseline;" style="box-sizing:inherit;font-size:15pt;font-family:Barlow, sans-serif;background-color:transparent;font-weight:700;font-variant-numeric:normal;font-variant-east-asian:normal;font-variant-alternates:normal;vertical-align:baseline">Avec cette équipe, nous avons l’expertise tant pour la recherche appliquée axée cancer, la connaissance de la récolte de propolis et la transformation de la propolis en produits naturels. </span></div><p><br /></p><p><br /></p><h3><span fr-original-style="color: rgb(250, 197, 28); font-size: 24px;" style="color:rgb(250, 197, 28);font-size:24px;box-sizing:inherit">SCIENCE AND BEES</span></h3><p><span fr-original-style="font-size: 18px;" style="font-size:18px;box-sizing:inherit">The laboratory of Francis Rodier, a researcher at the CRCHUM specializing in the exploration of cancer cell life and death in response to anticancer treatments, is partnering with Bee-O-Pharm to evaluate the potential use of <strong style="font-weight:700;box-sizing:inherit">propolis</strong>. This team will assess the impact of propolis on <strong style="font-weight:700;box-sizing:inherit">senescent cancer cells</strong>, a state of premature aging caused by chemotherapy, with the goal of enhancing the effectiveness of treatments and improving patients' quality of life by reducing side effects.</span></p><p><br /></p><h3><span fr-original-style="font-size: 18px;" style="font-size:18px;box-sizing:inherit"><strong style="font-weight:700;box-sizing:inherit"><span fr-original-style="color: rgb(250, 197, 28);" style="color:rgb(250, 197, 28);box-sizing:inherit">WHAT IS PROPOLIS?</span></strong></span></h3><p><span fr-original-style="font-size: 18px;" style="font-size:18px;box-sizing:inherit">Propolis is a resin harvested and transformed by bees, often referred to as <strong style="font-weight:700;box-sizing:inherit">the bees' own medicine</strong>. Bees produce propolis by mixing the resin with their wax and saliva, then use it to coat the entire interior of the hive. Some of the well-known properties of propolis include its <strong style="font-weight:700;box-sizing:inherit">antibacterial, antiviral, and antifungal</strong> potential, ensuring an optimal level of hygiene inside the hive.</span></p><h3><span fr-original-style="font-size: 18px;" style="font-size:18px;box-sizing:inherit"><strong style="font-weight:700;box-sizing:inherit"><span fr-original-style="color: rgb(250, 197, 28);" style="color:rgb(250, 197, 28);box-sizing:inherit">PROPOLIS: THE TREASURE OF BEES, A PROMISE FOR MEDICINE</span></strong></span></h3><p><span fr-original-style="font-size: 18px;" style="font-size:18px;box-sizing:inherit">Here are some of the proposed mechanisms of action of propolis, some of which will be scientifically validated through this research project:</span></p><ul><li style="font-size:18px"><strong style="font-weight:700;box-sizing:inherit">Inhibition of cell proliferation</strong>: Propolis can halt the cell cycle in cancerous tissues, thereby reducing the multiplication of malignant cells.</li><li style="font-size:18px"><strong style="font-weight:700;box-sizing:inherit">Induction of apoptosis</strong>: Certain compounds in propolis, such as <strong style="font-weight:700;box-sizing:inherit">artepillin C</strong>, promote apoptosis (programmed cell death) in cancer cells, helping to limit tumor progression.</li><li style="font-size:18px"><strong style="font-weight:700;box-sizing:inherit">Anti-angiogenic effect</strong>: Propolis may inhibit the formation of new blood vessels necessary for tumor growth, weakening the tumor by reducing its nutrient supply.</li><li style="font-size:18px"><strong style="font-weight:700;box-sizing:inherit">Anti-metastatic action</strong>: Studies suggest that propolis could help prevent and reduce both the number and volume of metastases, thereby limiting cancer spread.</li></ul><p><span fr-original-style="font-size: 18px;" style="font-size:18px;box-sizing:inherit">The <strong style="font-weight:700;box-sizing:inherit">first phase of this research project</strong> aims to confirm the effects of propolis on cancer cells using the <strong style="font-weight:700;box-sizing:inherit">advanced scientific platforms and expertise of the Institut du cancer de Montréal</strong>.</span></p><p><br /></p><p><span fr-original-style="font-size: 18px;" style="font-size:18px;box-sizing:inherit">With this team, we bring together <strong style="font-weight:700;box-sizing:inherit">strong expertise in applied cancer research, knowledge of propolis harvesting, and its transformation into natural health products</strong>.</span></p><p><br /></p></td></tr></tbody></table></td></tr></tbody></table></div></div></div></div>

<p style="margin:0px;line-height:1.5;box-sizing:inherit;color:rgb(0, 0, 0)">Bonjour <span data-custom-variable="{{firstname}}" fr-original-class="fr-deletable styled-tag-chip" fr-original-style style="background-color:rgb(248, 248, 255);border:1px solid rgb(191, 191, 255);border-radius:4px;color:rgb(42, 42, 196);padding:1px 8px;font-size:11px;display:inline-block;margin:0px;overflow-wrap:anywhere;user-select:none;box-sizing:inherit">Prénom</span>,</p><p style="margin:0px;line-height:1.5;box-sizing:inherit;color:rgb(0, 0, 0)"><br /></p><p style="margin:0px;line-height:1.5;box-sizing:inherit;color:rgb(0, 0, 0)">Nous vous remercions du fond du cœur de soutenir notre cause. Ce don contribue grandement à notre mission.<br /><br />Si vous souhaitez contribuer davantage à notre cause, contactez-nous pour devenir bénévole, ou parlez-en à votre entourage !<br /><br />Naomi Huck Ananou<br />naomi.huck-ananou@icm.qc.ca<br />5144659092</p>

<p>Bonjour <span class="fr-deletable styled-tag-chip" data-custom-variable="{{firstname}}">Prénom</span>,
    </p><p></p>
    <p>Nous vous remercions du fond du cœur de vous être inscrit pour collecter des fonds pour notre cause. Vos efforts auront un impact significatif, et nous sommes ravis de vous compter parmi notre équipe de collecte de fonds. 👏</p>
    <p></p>
    <p><strong>💡 Voici quelques conseils pour partager votre campagne:</strong></p>
    <ol>
    <li><strong>Personnalisez votre histoire :</strong> Expliquez pourquoi cette cause est importante pour vous. Les histoires personnelles ont plus de résonance auprès des donateurs potentiels.</li>
    <li><strong>Utilisez les médias sociaux :</strong> Publiez au sujet de votre campagne sur Facebook, Instagram, X et LinkedIn. Incluez le lien de la campagne et une image ou une vidéo convaincante.</li>
    <li><strong>Partagez par courriel :</strong> Envoyez un courriel personnel à vos amis, à votre famille et à vos collègues pour leur expliquer pourquoi vous collectez des fonds et comment ils peuvent vous aider.</li>
    <li><strong>Mises à jour régulières :</strong> Tenez vos supporters informés de vos progrès et des étapes que vous avez franchies. Ils resteront ainsi engagés et seront plus enclins à partager votre campagne.</li>
    </ol>
    <br />Naomi Huck Ananou<br />naomi.huck-ananou@icm.qc.ca<br />5144659092<br /><p></p>

<div><table><tbody><tr><td><table><tbody><tr><td><span>Projet Propo-Onco Project</span></td></tr></tbody></table></td></tr></tbody></table></div><div><br /></div><div><div><div><div><table><tbody><tr><td><table><tbody><tr><td><p style="margin:0px;line-height:1.5;box-sizing:inherit"><img src="https://res.cloudinary.com/hxn9dbuhd/image/upload/v1741012999/s4wuk4nk7rcdsijaqog7.png" alt="" style="position:relative;cursor:pointer;padding:0px 1px;user-select:none;box-sizing:inherit;max-width:100%" /><span>Science et abeilles</span></p><div><span>Le laboratoire de Francis Rodier, chercheur au CRCHUM qui se spécialise dans l’exploration de la vie et de la mort des cellules cancéreuses en réponse aux traitements anticancéreux, se joint à Bee-O-Pharm afin d'évaluer le potentiel d’utilisation de la « propolis ». Cette équipe évaluera l'impact de la propolis sur les cellules cancéreuses sénescentes, un état de vieillissement prématuré causé par la chimiothérapie, avec l'objectif d’améliorer l’efficacité des traitements eux-mêmes </span><span>et d'améliorer la qualité de vie des patients par la réduction des effets secondaires. </span></div><span><p style="box-sizing:inherit;margin:21.128pt 46.3994pt 0pt 0px;line-height:1.35014;letter-spacing:0.25px;text-indent:0.749626pt;text-align:justify"><span>QU’EST-CE QUE LA PROPOLIS?</span></p></span><div><span>La propolis est une résine récoltée et transformée par les abeilles qui constitue le « remède » des abeilles, leur propre médicament. Les abeilles fabriquent la propolis en mélangeant la résine à leur cire et leur salive, elles vont ensuite tapisser l’intérieur de la ruche entièrement de cette propolis. Certaines propriétés de la propolis bien connues aujourd’hui incluent son potentiel </span><span>anti bactérien, anti-viral et anti-fongique, </span><span>assurant ainsi un état de salubrité maximal à la ruche.  <br /></span></div><span><div><span>PROPOLIS : LE TRÉSOR DES ABEILLES, UNE PROMESSE POUR M </span></div><div><br /></div></span><div><span>Voici certains mécanismes d'action proposés de la propolis dont certains seront validés scientifiquement par le projet proposé:</span></div><span><ul><li><div><span>Inhibition de la prolifération cellulaire: La propolis peut arrêter le cycle cellulaire dans les tissus cancéreux, réduisant ainsi la multiplication des cellules malignes.</span></div></li><li><div><span>Induction de l'apoptose: Certains composés de la propolis, tels que l'artépilline C, favorisent l'apoptose (mort programmée) des cellules cancéreuses, contribuant à limiter la progression tumorale. </span></div></li><li><div><span>Effet anti-angiogénique: La propolis peut inhiber la formation de nouveaux vaisseaux sanguins nécessaires à la croissance tumorale, affaiblissant ainsi la tumeur en réduisant son apport en nutriments. </span></div></li><li><div><span>Action anti-métastatique: Des études suggèrent que la propolis pourrait prévenir et réduire le nombre et le volume des métastases, limitant la propagation du cancer. </span></div></li></ul><div><br /></div></span><div><span>Le projet de recherche vise dans un premier temps à confirmer l'action du propolis sur les cellules cancéreuses en utilisant les plateformes scientifiques et l’expertise bien établies de l’Institut du cancer de Montréal. </span></div><div><br /></div><div><span>Avec cette équipe, nous avons l’expertise tant pour la recherche appliquée axée cancer, la connaissance de la récolte de propolis et la transformation de la propolis en produits naturels. </span></div><p><br /></p><p><br /></p><p style="font-weight:bold"><span>SCIENCE AND BEES</span></p><p><span>The laboratory of Francis Rodier, a researcher at the CRCHUM specializing in the exploration of cancer cell life and death in response to anticancer treatments, is partnering with Bee-O-Pharm to evaluate the potential use of <strong>propolis</strong>. This team will assess the impact of propolis on <strong>senescent cancer cells</strong>, a state of premature aging caused by chemotherapy, with the goal of enhancing the effectiveness of treatments and improving patients' quality of life by reducing side effects.</span></p><p><br /></p><p style="font-weight:bold"><span><strong><span>WHAT IS PROPOLIS?</span></strong></span></p><p><span>Propolis is a resin harvested and transformed by bees, often referred to as <strong>the bees' own medicine</strong>. Bees produce propolis by mixing the resin with their wax and saliva, then use it to coat the entire interior of the hive. Some of the well-known properties of propolis include its <strong>antibacterial, antiviral, and antifungal</strong> potential, ensuring an optimal level of hygiene inside the hive.</span></p><p style="font-weight:bold"><span><strong><span>PROPOLIS: THE TREASURE OF BEES, A PROMISE FOR MEDICINE</span></strong></span></p><p><span>Here are some of the proposed mechanisms of action of propolis, some of which will be scientifically validated through this research project:</span></p><ul><li><strong>Inhibition of cell proliferation</strong>: Propolis can halt the cell cycle in cancerous tissues, thereby reducing the multiplication of malignant cells.</li><li><strong>Induction of apoptosis</strong>: Certain compounds in propolis, such as <strong>artepillin C</strong>, promote apoptosis (programmed cell death) in cancer cells, helping to limit tumor progression.</li><li><strong>Anti-angiogenic effect</strong>: Propolis may inhibit the formation of new blood vessels necessary for tumor growth, weakening the tumor by reducing its nutrient supply.</li><li><strong>Anti-metastatic action</strong>: Studies suggest that propolis could help prevent and reduce both the number and volume of metastases, thereby limiting cancer spread.</li></ul><p><span>The <strong>first phase of this research project</strong> aims to confirm the effects of propolis on cancer cells using the <strong>advanced scientific platforms and expertise of the Institut du cancer de Montréal</strong>.</span></p><p><br /></p><p><span>With this team, we bring together <strong>strong expertise in applied cancer research, knowledge of propolis harvesting, and its transformation into natural health products</strong>.</span></p><p><br /></p></td></tr></tbody></table></td></tr></tbody></table></div></div></div></div>

Propolis: la science des abeilles - Science and Bees

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Institut du cancer de Montréal

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2. **Type of Activities**:
   - **Fundraising Events**: The ICM organizes various fundraising events, including the "DÉFI Respire," an annual run that raises funds for thoracic oncology research. This event has been running since 2010 and has successfully raised over $771,000 to support research projects.
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Institut du cancer de Montréal

Propolis: la science des abeilles - Science and Bees

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