CanNRT | CanFRN

### Context Profile for CanNRT | CanFRN

#### 1. Organization Mission & Cause
CanNRT (Canadian Network of Rehabilitation and Disability Research) and CanFRN (Canadian Disability Research Network) aim to enhance the quality of life for individuals with disabilities through research, knowledge translation, and community engagement. Their mission focuses on bridging the gap between research and practice, ensuring that disability-related data and insights are effectively utilized to inform policies and improve services for people with disabilities.

#### 2. Type of Activities
- **Research Forums**: Regularly organized events such as the "CanNRT Research Forum," which addresses challenges in collecting disability-related data.
- **Journal Clubs**: Monthly discussions (e.g., "CanNRT Journal Club") focusing on knowledge translation to policy.
- **Membership Programs**: Opportunities for individuals and organizations to join CanNRT and TACC (Translating Research into Action for Community) to access exclusive events and resources.
- **Community Engagement**: Initiatives aimed at fostering collaboration among researchers, practitioners, and individuals with disabilities.

#### 3. Tone of Voice
The tone of voice used by CanNRT is professional yet approachable. Communications are informative and supportive, aiming to inspire action and engagement from their audience. The language is clear and direct, with a focus on inclusivity and community building.

#### 4. Emoji Usage
The website and email communications do not prominently feature emojis. The tone remains formal and professional, which aligns with the nature of their work in research and policy.

#### 5. Key Facts
- **Founding Info**: Specific founding details are not provided on the website, but the organization is active in the Canadian disability research community.
- **Scale**: CanNRT has conducted 30 forms and sent out 78 email campaigns, indicating a robust engagement strategy.
- **Impact Metrics**: While specific metrics are not detailed, the organization emphasizes the importance of data collection and knowledge translation to improve services for individuals with disabilities.
- **Volunteer Info**: Information on volunteer opportunities is not explicitly mentioned, but membership programs suggest avenues for community involvement.

#### 6. Writing Guidelines
- **Clarity and Brevity**: Ensure that content is straightforward and easy to understand, avoiding jargon where possible.
- **Professional Tone**: Maintain a professional yet friendly tone that encourages engagement and participation.
- **Inclusive Language**: Use language that is inclusive and respectful of all individuals, particularly those with disabilities.
- **Call to Action**: Include clear calls to action in communications, encouraging readers to participate in events, join as members, or engage with research findings.

This context profile serves as a foundational guide for creating personalized content that aligns with CanNRT's mission, values, and communication style.

General admission

Votre billet électronique

<p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Bonjour <span contenteditable="false" data-custom-variable="{{firstname}}" fr-original-class="fr-deletable styled-tag-chip " fr-original-style style="background-color:rgb(248, 248, 255);border:1px solid rgb(191, 191, 255);border-radius:4px;color:rgb(42, 42, 196);display:inline-block;margin:0px;padding:1px 8px;font-size:11px;line-height:16px;overflow-wrap:anywhere;user-select:none;box-sizing:inherit">First name</span> ,</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Nous vous remercions de vous être inscrit(e) au <strong style="font-weight:700;box-sizing:inherit">Forum de recherche RTSA-Q1K</strong> qui se tiendra le 29 mai 2024 à 16h00 HAE.</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Veuillez nous rejoindre en ligne en utilisant le <strong style="font-weight:700;box-sizing:inherit">lien </strong><strong style="font-weight:700;box-sizing:inherit">Zoom </strong>suivant : <a href="https://mcgill.zoom.us/j/81463218346?pwd=azh2ZzN3blpDcitFT0YwbFU2MFVMQT09" style="color:green;text-decoration:inherit;user-select:auto;font-weight:700;box-sizing:inherit">https://mcgill.zoom.us/j/81463218346?pwd=azh2ZzN3blpDcitFT0YwbFU2MFVMQT09</a></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><strong style="font-weight:700;box-sizing:inherit">ID de réunion</strong> : 814 6321 8346 </p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><strong style="font-weight:700;box-sizing:inherit">Code</strong> : 509638</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Si vous avez des questions ou si vous avez besoin d'aménagements spécifiques, veuillez nous contacter à l'adresse <a href="mailto:rtsa-tacc@mcgill.ca" style="color:inherit;text-decoration:inherit;user-select:auto;box-sizing:inherit">rtsa-tacc@mcgill.ca</a>.</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Cordialement,</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">L'équipe du RTSA</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Site Web : <a style="color:green;text-decoration:inherit;user-select:auto;font-weight:700;box-sizing:inherit">www.rtsa-tacc.com</a></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><a href="https://rtsa-tacc.info/m/suivez-nous" style="color:green;text-decoration:inherit;user-select:auto;font-weight:700;box-sizing:inherit">Suivez-nous sur les réseaux sociaux</a></p>

<div><div><span><span>Aperçu</span></span></div></div><div><div><span><span>Format </span></span><span><span>: Virtuel (via Zoom)</span></span></div></div><div><div><span><span>Conférencier.e.s</span></span><span><span>: Christian O'Reilly, Ph.D., M.Sc., B.Eng., Professeur adjoint, Département d'informatique et d'ingénierie, University of South Carolina, et Diksha Srishyla, M.Sc., Étudiante au doctorat, University of South Carolina</span></span></div></div><div><div><span><span>Date </span></span><span><span>: Mercredi 29 mai 2024</span></span></div></div><div><div><span><span>Heure </span></span><span><span>: 16h00 - 17h00 HAE</span></span></div></div><div><div><span><br /></span></div></div><div><div><span><span>Joignez-vous à nous pour le Forum de recherche RTSA-Q1K, présentant une présentation virtuelle qui explore la recherche à l'intersection des conditions neurodéveloppementales et des technologies de pointe. Le Dr Christian O'Reilly dirigera une présentation sur la "Batterie de tests expérimentaux EEG/suivi oculaire Q1K", tandis que l'étudiante au doctorat Diksha Srishyla de l'Université de South Carolina présentera "Validation des données de suivi oculaire du réflexe de la lumière pupillaire dans le cadre du projet pilote Q1K".</span></span></div></div><div><div><span><br /></span></div></div><div><div><span><span>Ce Forum explorera de nouvelles méthodes et découvertes de l'initiative Québec 1000 Familles (Q1K), offrant des informations importantes sur l'autisme et les conditions neurodéveloppementales connexes.</span></span></div></div><div><div><span><br /></span></div></div><div><div><span><span>Ouvert à toutes et tous, l'inscription est requise pour participer à cet événement captivant.</span></span></div></div><div><br /></div><div><div><span><span>Résumés</span></span></div></div><div><div><span><span>La batterie de tests expérimentaux EEG et de suivi oculaire de l’initiative Q1K</span></span></div></div><div><div><span><span>L'initiative Québec 1000 Familles (Q1K) est une grande cohorte de familles ayant au moins un membre atteint du trouble du spectre autistique ou d'une condition neurodéveloppementale connexe. Elle a été développée comme un projet en trois phases, avec une profondeur de phénotypage croissante de la première phase (registre de recherche) à la troisième phase (phénotypage approfondi). La phase ultime s'appuie sur des données démographiques collectées, des questionnaires et des échantillons biologiques pour une évaluation génétique et ajoute un phénotypage approfondi multi-modalités, comprenant des données EEG haute densité, suivi oculaire, comportementales et IRM. Dans cette présentation, le Dr O'Reilly se concentrera sur la batterie de tests expérimentaux EEG/suivi oculaire développée par l'équipe expérimentale Q1K. Il discutera de notre approche générale et de notre philosophie de conception, du système et de son intégration EEG/suivi oculaire multi-modalités, des tâches, et de leur validation préliminaire. Il conclura en discutant des orientations futures, y compris la publication en libre accès de cette batterie de tests expérimentaux pour soutenir la normalisation des tâches et le regroupement de données multi-projets dans l'autisme.</span></span></div></div><div><div><span><br /></span></div></div><div><div><span><span>Validation des données de suivi oculaire du réflexe de la lumière pupillaire dans le cadre du projet pilote Q1K</span></span></div></div><div><div><span><span>Le réflexe de la lumière pupillaire (RLP) évalue la fonction autonome en mesurant le diamètre de la pupille en réaction à un stimulus lumineux. Sept études ont précédemment utilisé le RLP dans le contexte de l'autisme. Au cours de l'essai pilote de l'étude Québec 1000 (Q1K), nous avons administré le RLP ainsi qu'une batterie d'autres tâches de suivi oculaire en utilisant un suivi oculaire à distance. Nous avons validé les résultats de la tâche RLP dans notre essai pilote Q1K en comparant nos résultats à ceux d'autres études ayant utilisé des pupillomètres quantitatifs dans des paramètres cliniques (Kim et al. 2022). Plus précisément, nous avons calculé la latence. Il s'agit du temps nécessaire à la pupille pour commencer à se contracter en réaction au stimulus lumineux. Nous avons calculé une RLP moyenne de 0,33 +/- 0,053 s. Ceci est supérieur à la latence moyenne calculée par les pupillomètres quantitatifs (0,24-0,28 s). Nous discutons de notre méthodologie de calcul et des améliorations potentielles.</span></span></div></div><div><div><span><br /></span></div></div><div><div><span><span>Biographies des conférencier.e.s</span></span></div></div><div><div><span><span>Christian O’Reilly </span></span><span><span>a obtenu son B.Ing. (génie électrique ; 2007), sa M.Sc.A. (génie biomédical ; 2011) et son Ph.D. (génie biomédical ; 2012) de l'École Polytechnique de Montréal, où il a appliqué la reconnaissance de motifs et l'apprentissage automatique pour prédire les risques d'accident vasculaire cérébral. Il a ensuite été chercheur postdoctoral au Centre de recherche avancée en médecine du sommeil de l'Hôpital du Sacré-Cœur/Université de Montréal (2012-2014), puis chercheur postdoctoral du CRSNG au Centre d'imagerie cérébrale de McGill (2014-2015) où il a travaillé sur la caractérisation des transitoires du sommeil EEG, leurs sources et leur connectivité fonctionnelle. Au cours de cette période, il a également été chercheur invité dans le laboratoire du professeur K. Friston à l'University College de Londres pour étudier la connectivité effective pendant les transitoires du sommeil en utilisant l'approche de modélisation causale dynamique. Il a ensuite effectué un stage de six mois auprès du professeur M. Elsabbagh sur la connectivité fonctionnelle dans l'autisme, après quoi il a déménagé en Suisse pour travailler pour le projet de renommée internationale Blue Brain (EPFL ; 2015-2018), où il a dirigé le projet de modélisation détaillée à grande échelle de la boucle thalamocorticale. En 2020, il a repris sa collaboration avec le Dr Elsabbagh en tant qu'associé de recherche au Centre Azrieli de recherche sur l'autisme (McGill), où il a étudié la connectivité cérébrale dans l'autisme et les troubles neurodéveloppementaux connexes. Depuis 2021, Christian a rejoint le département d'informatique et d'ingénierie, l'Institut d'intelligence artificielle, l'Institut pour l'esprit et le cerveau, et le Centre de recherche sur l'autisme et le neurodéveloppement de la Caroline à l'Université de la Caroline du Sud en tant que professeur adjoint. Il a présidé le Groupe expérimental Q1K de 2020 à 2024.</span></span></div></div><div><div><span><br /></span></div></div><div><div><span><span>Diksha Srishyla</span></span><span><span> est étudiante au doctorat sous la supervision de Christian O’Reilly à l'Université de la Caroline du Sud.</span></span></div></div><div><div><span><br /></span></div></div><div><div><span><span>À propos du Forum de recherche RTSA-Q1K :</span></span></div></div><div><div><span><span>Les Forums de recherche RTSA-Q1K mettent en valeur le travail diversifié des membres de TACC et Q1K, et favorisent les opportunités de collaboration et d'échange de connaissances autour des travaux en cours dans la recherche neurodéveloppementale et à travers les disciplines.</span></span></div></div>

Forum de recherche RTSA-Q1K

<p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Hello <span contenteditable="false" data-custom-variable="{{firstname}}" fr-original-class="fr-deletable styled-tag-chip " fr-original-style style="background-color:rgb(248, 248, 255);border:1px solid rgb(191, 191, 255);border-radius:4px;color:rgb(42, 42, 196);display:inline-block;margin:0px;padding:1px 8px;font-size:11px;line-height:16px;overflow-wrap:anywhere;user-select:none;box-sizing:inherit">First name</span> ,</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Thank you for registering for the <strong style="font-weight:700;box-sizing:inherit">TACC-Q1K Research Forum on May 29, 2024 at 4:00 p.m. EDT.</strong></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Please join us online at the following <strong style="font-weight:700;box-sizing:inherit">Zoom link</strong>: </p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><a href="https://mcgill.zoom.us/j/81463218346?pwd=azh2ZzN3blpDcitFT0YwbFU2MFVMQT09" style="color:green;text-decoration:inherit;user-select:auto;font-weight:700;box-sizing:inherit">https://mcgill.zoom.us/j/81463218346?pwd=azh2ZzN3blpDcitFT0YwbFU2MFVMQT09</a></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><strong style="font-weight:700;box-sizing:inherit">Meeting ID:</strong> 814 6321 8346</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><strong style="font-weight:700;box-sizing:inherit">Passcode</strong>: 509638</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Should you have any questions or require specific accommodations, please contact us at <a href="mailto:rtsa-tacc@mcgill.ca" style="color:green;text-decoration:inherit;user-select:auto;font-weight:700;box-sizing:inherit">rtsa-tacc@mcgill.ca</a>. </p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Regards,</p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">The TACC Team </p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><br /></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit">Website: <a href="http://www.rtsa-tacc.com" style="color:green;text-decoration:inherit;user-select:auto;font-weight:700;box-sizing:inherit">www.rtsa-tacc.com </a></p><p style="width:100%;margin-top:0px;margin-bottom:0px;box-sizing:inherit"><a href="https://rtsa-tacc.info/m/suivez-nous" style="color:green;text-decoration:inherit;user-select:auto;font-weight:700;box-sizing:inherit">Follow us on social media</a></p>

<p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><u><strong><span>Overview</span></strong></u></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>Format</strong>: Virtual (via Zoom)</span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>Speaker(s): Christian O'Reilly, Ph.D., M.Sc., B.Eng., </strong>Assistant Professor, Department of Computer Science and Engineering, University of South Carolina, and <strong>Diksha Srishyla, M.Sc., </strong>PhD Student, University of South Carolina</span><br /><br /></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>Date: </strong>Wednesday, May 29, 2024</span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>Time: </strong>4 - 5 p.m. EDT</span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><br /></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>Join us for the TACC-Q1K Research Forum, featuring a virtual presentation that explores research at the intersection of neurodevelopmental conditions and cutting-edge technology. Dr. Christian O'Reilly will lead a presentation on the "Q1K EEG/Eye-Tracking Experimental Test Battery," while PhD student Diksha Srishyla from the University of South Carolina will present "Pupillary Light Reflex Eye-Tracking Data Validation from the Q1K Pilot."</strong></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><br /></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>This Forum will explore new methods and findings from the Quebec 1000 Families (Q1K) initiative, offering important insights into autism and related neurodevelopmental conditions.</strong></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><br /></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>Open to all, registration is required to participate in this engaging event.</strong></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><br /></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><u><strong>Abstracts:</strong></u></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><em><strong>The Q1K EEG/Eye-Tracking Experimental Test Battery</strong></em></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span>The Quebec 1000 Families (Q1K) initiative is a large cohort of families with at least one member with autism spectrum disorder or a related neurodevelopmental condition. It has been developed as a three-phase project, with increasing phenotyping depth from the first phase (research registry) to the third phase (deep phenotyping). The ultimate phase builds on collected demographics, questionnaires, and biosamples for genetic assessment and adds multi-modal deep phenotyping including high-density EEG, eye tracking, behavioral, and MRI data. In this talk, Dr. O'Reilly will focus on the EEG/Eye-Tracking experimental test battery developed by the Q1K Experimental Team. He will discuss our general approach and design philosophy, the system and its multi-modal EEG/Eye-Tracking integration, the tasks, and their preliminary validation. He will conclude by discussing future directions, including the open-access release of this experimental test battery to support task standardization and multi-project data pooling in autism.</span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><br /></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><em><strong>Pupillary light reflex eye-tracking data validation from the Q1K pilot</strong></em></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span>The pupillary light reflex (PLR) assesses autonomic function by measuring pupil diameter in reaction to a light stimulus. 7 studies have previously used the PLR in the context of autism. During the pilot trial of the Quebec 1000 (Q1K) study, we administered the PLR along with a battery of other eye-tracking tasks using a remote eye-tracker. We validated results from the PLR task in our Q1K pilot trial by comparing our results with those from other studies that utilized quantitative pupillometers in clinical settings (Kim et al. 2022). Specifically, we calculated the latency. This is the time taken by the pupil to start constricting in reaction to the light stimulus. We calculated an average PLR of 0.33 +/- 0.053 s. This is higher than the average latency calculated by quantitative pupillometers (0.24-0.28 s). We discuss our calculation methodology and potential improvements.</span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><br /></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><u><strong>Speaker Biographies:</strong></u></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>Christian O’Reilly </strong>received his B.Ing (electrical eng.; 2007), his M.Sc.A. (biomedical eng.; 2011), and his Ph.D. (biomedical eng.; 2012) from the École Polytechnique de Montréal where he applied pattern recognition and machine learning to predict brain stroke risks. He was later a postdoctoral fellow at the Center for Advanced Research in Sleep Medicine of the Hôpital du Sacré-Coeur/Université de Montréal (2012-2014) and then an NSERC postdoctoral fellow at McGill's Brain Imaging Center (2014-2015) where he worked on characterizing EEG sleep transients, their sources, and their functional connectivity. During this period, he also was a visiting scholar in Pr. K. Friston's laboratory at the University College of London to study effective connectivity during sleep transients using the Dynamic Causal Modelling approach. He later took on a six-month fellowship with the Pr. M. Elsabbagh on functional connectivity in autism after which he moved to Switzerland to work for the internationally renowned Blue Brain project (EPFL; 2015-2018) where he led the project on large-scale biophysically-detailed modeling of the thalamocortical loop. In 2020, he resumed his collaboration with Dr. Elsabbagh as a research associate at the Azrieli Centre for Autism Research (McGill) where he studied brain connectivity in autism and related neurodevelopmental disorders. Since 2021, Christian joined the Department of Computer Science and Engineering, the Artificial Intelligence Institute, the Institute for Mind and Brain, and the Carolina Autism and Neurodevelopmental Research Center at the University of South Carolina as an assistant professor. He chaired the Q1K Experimental Group from 2020 to 2024.</span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><br /></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><strong>Diksha Srishyla</strong> is a PhD student under the supervision of Christian O’Reilly at the University of South Carolina.</span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><br /></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span><u><strong>About the TACC-Q1K Research Forum:</strong></u></span></p><p style="border:0px;margin:0px;outline:0px;padding:0px;vertical-align:baseline;min-height:1.5em;font-style:normal;font-variant-ligatures:normal;font-variant-caps:normal;font-weight:400;letter-spacing:normal;orphans:2;text-align:left;text-indent:0px;text-transform:none;widows:2;word-spacing:0px;-webkit-text-stroke-width:0px;white-space:normal;text-decoration-thickness:initial;text-decoration-style:initial;line-height:1;box-sizing:inherit;max-width:100%"><span>TACC-Q1K Research Forums showcase the diverse work of TACC and Q1K members, and foster opportunities for collaboration and knowledge exchange around ongoing work in neurodevelopmental research and across disciplines.</span></p>

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