The Upstream Grant Fund supports organizations tackling global challenges such as disaster prevention, health emergencies, and strengthening human connection.

Organization must align with upstream priorities (disaster prevention, health emergencies, strengthening human connection)

Upstream Grants

A 2026 open call accepting pre-applications from U.S. charitable organizations for work aligned to the Foundation's focus areas: Global Health, K-12 STEM Education, and Economic Mobility (with programmatic priorities including Marion County, IN for K-12 and economic mobility).

Lilly Foundation Open Call 2026

The Foundation funds projects that expand access to financial education, affordable housing, and children’s health in its service area.

Applicant must be an organization (not an individual)

GreenState Foundation Grants

Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional)

Resident-led grants awarded by the Resident Advancement Committee for neighborhood projects (gardens, pocket parks, mentoring, etc.); neighbors and small nonprofits within Saint Luke’s footprint can receive up to $6,000.

Applicant must be a resident of Buckeye–Shaker, Mt. Pleasant, or Woodland Hills | If applicant is not a 501(c)(3), must collaborate with a fiscal sponsor (501(c)(3)) | Available March–September annually

Upstream Grants

About this program

Eligibility

Contact & website

Carrie Varoquiers

[email protected]

www.workday.com

Past recipients

2024

Year Up Inc

$1,000,000

Generation - You Employed Inc

$800,000

Per Scholas Inc

$500,000

Jobs For The Future Inc

$350,000

Inco Community Inc

$250,000

Opportunity At Work Inc

$250,000

Rockefeller Philanthropy Advisors Inc

$250,000

Goodness Village

$200,000

Coalfield Development Corporation

$150,000

Rolling

~$50K (308 grants)

National · All 50 states

Similar Grants

Lilly Foundation Open Call 2026

~$92K

GreenState Foundation Grants

~$5K

Advancing HIV/AIDS Research within the Mission of the NIDCD (R01 Clinical Trial Optional)

~$820K

Community Grants

Up to $6.0K

Translational Research in Maternal and Pediatric Pharmacology and Therapeutics (R21 Clinical Trial Optional)

~$820K

FY27 Cost Sharing Capital Grants (Stage 2)