The Caine Family Foundation

Restricted Access
Private Foundation
Wilmington, DelawareMicroEIN: 453233150
Jewish OrganizationsCancer Research CentersHealth CharitiesHuman ServicesCommunity Service Clubs

This organization is a private foundation dedicated to supporting a variety of causes, with a notable emphasis on Jewish organizations and health-related initiatives, particularly cancer research. Its mission reflects a commitment to philanthropy that addresses both community needs and specific health challenges. The foundation provides funding to diverse recipients, including local safety net services, educational campaigns, and emergency response efforts. It actively supports both general and unrestricted grants, indicating a flexible approach to funding that allows recipients to address their unique challenges. The foundation's activities demonstrate a strong focus on enhancing the well-being of communities and individuals, particularly within the Jewish community.

Source: Zeffy Agent · Mar 2026

Ideal Applicant

Organizations that fit the foundation’s observed giving pattern: small to mid-size charities or campaigns (often local or regional), organizations aligned with Jewish community causes, health/cancer research, disaster/emergency campaigns, or community service groups that can be introduced via a personal or institutional connection.

Good Fit

  • Existing relationship, referral, or introduction to a trustee or close intermediary.
  • Alignment with Jewish communal giving, health research, or local community service work.
  • Need for a small unrestricted or project grant (typical 2023 grants clustered around $1K).
  • Ability to demonstrate immediate impact or a clear, campaign-style funding need (e.g., emergency campaigns).

Geography

Broad

Latest observed grants were distributed across nine states, demonstrating a multi-state footprint, though nearly half of dollars went to Florida.

Recipient Variety

Broad

The most recent year included 18 distinct recipients and 23 grants across diverse issue areas (Jewish organizations, cancer research, environmental groups, emergency campaigns), indicating a broadly varied recipient set for the foundation’s size.

New Applicants

Restrictive

Direct evidence of recipient turnover exists (13 new recipients in the latest year), but the foundation states it funds only preselected recipients and has no public website or visible submission/contact route, so unfamiliar applicants are unlikely to enter the portfolio without an invitation or referral.

Source: Zeffy Agent · Mar 2026