Robert J & Helen C Kleberg Foundation
The Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation is a San Antonio-based private foundation supporting medical and basic science research, conservation, community services, and the arts. The site publishes grant guidelines, recent news, and links to the online application portal and deadlines.
Source: Website · Mar 2026
Ideal Applicant
Organizations conducting biomedical or basic science research (universities, medical centers, research institutes) and Texas-based nonprofits with programmatic community, arts, conservation, or youth work; applicants should present a clear project budget and nontechnical project description.
Good Fit
- • Established biomedical research program or medical center affiliation
- • Clear project budget and nontechnical summary presented on institutional letterhead
- • Track record of prior grants or repeat funding from foundations
- • Based in or serving South Texas for non-research requests
- • Capacity to manage mid-to-large grants (six-figure to multi-million)
Geography
Grants are multi-state (seven states observed) but giving is regionally concentrated: Texas accounted for roughly 62% of dollars and the majority of grant counts in the latest year.
Recipient Variety
The foundation funded a large and diverse set of recipients in the latest year (47 distinct recipients) with both major research institutions and many smaller community, arts, and conservation organizations; repeat and new recipients both appear in the portfolio.
New Applicants
Direct evidence supports entry by unfamiliar applicants: the foundation publishes guidelines and an online portal, and 18 new recipients appeared in 2024 (about 38% of that year's recipients), so new entrants have a realistic path into the portfolio.
Source: Zeffy Agent · Mar 2026
