The Six Four Foundation

Restricted Access
Private Foundation
LEWISVILLE, TexasLargeEIN: 980364976
Cancer Research CentersHealth CharitiesEducation NonprofitsHuman ServicesInternational Relief Agencies

This organization is a private foundation dedicated to supporting a range of charitable causes. Its mission appears to focus on health-related initiatives, particularly cancer research, as evidenced by significant grants to organizations like the Prostate Cancer Foundation and Dana-Farber Cancer Institute. Additionally, it supports educational nonprofits and human services, reflecting a commitment to improving community well-being. The foundation also engages in international relief efforts, indicating a broader humanitarian focus. Through its unrestricted program grants, it serves various populations and sectors, demonstrating a flexible approach to funding that allows recipients to allocate resources as needed.

Source: Zeffy Agent · Mar 2026

Ideal Applicant

Established health, cancer-research, education, or India-related nonprofits with program scale and visibility, or organizations connected to the foundation’s existing grantees or networks.

Good Fit

  • Clear program alignment with cancer research, major health charities, higher education, or India-focused international work.
  • Established track record and capacity to manage multi-year, unrestricted program grants.
  • Existing relationships or introductions from current grantees, board members, or other trusted intermediaries.
  • Geographic presence or program impact in California or other states the foundation has previously funded.

Geography

Broad

Grants in the latest year reached recipients in seven different states, showing a multi-state footprint, though roughly two-thirds of dollars were concentrated in California.

Recipient Variety

Moderate

The foundation funded 15 distinct organizations in 2023 (17 in 2022), indicating a moderately broad recipient set for its size, but dollars are highly concentrated among a few large grantees.

New Applicants

Restrictive

The foundation explicitly funds only preselected applicants and filings show high dollar concentration to repeat major grantees; although several new recipients appeared in 2023, new entrants likely join by invitation or referral rather than open application.

Source: Zeffy Agent · Mar 2026